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Polapril 28 capsl 5mg Ramipril Полаприл Arterial hypertension treatment

Product sku: MD1067

Availability: In stock

Only 35 left


Quick Overview

Arterial hypertension treatment



Polapril Indications

- Arterial hypertension, to reduce blood pressure as monotherapy or in combination with other antihypertensive agents such as diuretics, and calcium antagonists.

- Congestive heart failure; in combination with a diuretic.

- Congestive heart failure during the first few days after an acute myocardial infarction.

- Non-diabetic or diabetic nephropathy, glomerular or initial.

- Reducing the risk of myocardial infarction, stroke or cardiovascular death in patients at increased cardiovascular risk as a result of the presence of coronary artery disease (with or without myocardial infarction), stroke, peripheral vascular disease history or diabetes mellitus with at least one additional factor of heart -sosudistogo risk (microalbuminuria, hypertension, elevated total cholesterol levels, low HDL cholesterol, smoking).


Dosage & Administration

Applied inside.
Dosage assigned physician individually in accordance with the effect and tolerability.
Polapril recommended to be taken every day at the same time. It can be applied regardless of the meal. The capsules should be swallowed whole with plenty of water (about 0.5 cups).

Treatment of hypertension
The recommended starting dose for adults - 2.5 mg of Polapril 1 time per day.
Depending on the patient's response the dose can be increased by doubling every 2-3 weeks.
Usual maintenance dose - 2.5-5 mg of Polapril per day.
The maximum daily dose for adults - 10 mg of Polapril.
An alternative to increasing the dose to 5 mg per day of Polapril additional application may be, for example, a diuretic or a calcium antagonist.

Treatment of congestive heart failure
The recommended starting dose for adults - 1.25 mg of Polapril 1 time per day.
Depending on the patient's response the dose can be increased by doubling every 1-2 weeks. If necessary, the dose is 2.5 mg Polaprila or higher, it can be taken as a single dose or divided into 2 doses.
The maximum daily dose - 10 mg Polapril.

Treatment after myocardial infarction
The recommended starting dose of - 5 mg Polaprila per day, divided into 2 doses of 2.5 mg; one dose taken in the morning, and the other - in the evening. If the patient does not tolerate this initial dosage recommended dose of 1.25 mg 2 times a day for 2 days.

Then, depending on the patient response, dosage may be increased by doubling every 1-3 days.
Subsequently, the total daily dose which is divided into two first reception can be taken as a single.
The maximum daily dose - 10 mg Polaprila.

Experience of treatment of patients with severe (grade IV classification NYHA) heart failure immediately after myocardial infarction is not enough. In the case of Polapril drug it is recommended to start therapy with the lowest effective daily dose (1.25 mg Polaprila 1 time per day) and any subsequent increase in its spending with extreme caution.



- hypersensitivity to ramipril, other ACE inhibitors or components of the drug;

- angioedema in history (hereditary / idiopathic or due to previous therapy with ACE inhibitors or angiotensin II receptor antagonists);

- renal artery stenosis (bilateral or stenosis of the artery to a solitary kidney);

 -hypotensive or haemodynamically unstable states; primary aldosteronism;

- during pregnanc, lactation, childhood.

Polapril should be avoided or other ACE inhibitors in combination with extracorporal methods of therapy, which can cause blood contacting with the negatively charged surfaces because when there is a risk of severe anaphylactoid reaction that sometimes may lead to the development of severe anaphylactic shock.

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